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PCI MNL-141-12 describes the basic process of blast-resistant structural design for precast/prestressed concrete components. It includes calculating blast loads on the component, determining the dynamic response of the component, checking the response against specified performance criteria, designing the component connections, and checking the component for adequate shear capacity. The emphasis in this manual is on blast loads from exterior explosions and the dynamic analysis of blast-loaded structural components idealized as equivalent single degree of freedom systems. These assumptions simplify the blast-resistant design procedure discussed in this manual, but they apply to many cases of practical interest for anti-terrorism and force protection design.